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NAD+ and NMN: what is the difference?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme the cells use to make energy. NMN (nicotinamide mononucleotide) is one step before it: the body converts NMN into NAD+.
| NAD+ | NMN | |
|---|---|---|
| Usual route | Injection (IV or SQ) or nasal spray | Capsules by mouth |
| Taken by mouth | Largely broken down in the gut before it is absorbed | Absorbed and may help raise NAD+ levels |
| Possible side effects | By IV: flushing, chest tightness, nausea or headache, mostly when infused quickly. By SQ: stinging | Generally well tolerated; occasionally mild stomach upset or headache |